I-Fentanyl ibulala ngisho nakakhulu uma ixutshwe ne-xylazine (noma i-‘tranq’): Okufanele ukwazi manje

Iningi labantu lizwile nge-fentanyl, i-opioid yokwenziwa enamandla ngokuphindwe izikhathi ezingama-50 kune-heroin futhi inembangela enkulu yokufa kwabantu abangaphezu kuka-150 ngosuku, ngokweCenters for Disease Control and Prevention (CDC).

Kodwa manje sekuvele umuthi omusha lokho kwenza i-fentanyl ibe yingozi nakakhulu.

I-Drug Enforcement Agency (DEA) ikhiphe isexwayiso sokuphepha komphakathi mayelana ne-xylazine – ebuye yaziwa ngegama layo lomgwaqo elithi “Tranq” – eya ngokuya ixutshwa ne-fentanyl.

“I-Xylazine yenza usongo lwezidakamizwa oluyingozi kunazo zonke izwe lethu elake labhekana nalo, i-fentanyl, ngisho nokufa kakhulu,” kusho u-Anne Milgram, umqondisi, esitatimendeni se-DEA.

I-DEA IKHALA ISEXWAYISO ESIQINISEKISO NGE-FENTANYL ESIXHISWA NENYAMA ‘TRANQ’ ZOMBIE UMUTHI OSHAnjwe EZINGA-48 KWAMA-50

“I-DEA ibambe izingxube ze-xylazine ne-fentanyl ezifundeni ezingu-48 kwezingu-50. I-DEA Laboratory System ibika ukuthi ngo-2022, cishe u-23% we-fentanyl powder kanye no-7% wamaphilisi e-fentanyl athathwe yi-DEA aqukethe i-xylazine.”

Nakhu okumele ukwazi ngalesi sidakamizwa esiyingozi.

Kuhloswe ukuthi kusetshenziswe njengomuthi wezilwane

I-Xylazine yavunywa ekuqaleni ku-1972 ukuze isetshenziswe odokotela bezilwane njenge-sedative, i-pain reliever kanye / noma i-muscle relaxer, ngokusho kwe-DEA.

Ivamise ukusetshenziswa ezilwaneni ezinkulu nezincane ukuze zizolise ngaphambi kokuhlolwa nokuhlinzwa. Ingasetshenziswa futhi njengesidambisi sobuhlungu noma isibulali-zinzwa sasendaweni.

Ukufa kwe-Xylazine ngokweqile kuyenyuka - okunomthelela omkhulu kakhulu owenzeka enyakatho-mpumalanga ye-United States.

Ukufa kwe-Xylazine ngokweqile kuyenyuka – okunomthelela omkhulu kakhulu owenzeka enyakatho-mpumalanga ye-United States. (iStock)

URob Louie, iphini likamongameli omkhulu wezinsizakalo zomtholampilo e-RemedyOne eNew Yorkiveza ukuthi i-xylazine inamandla ngokwedlulele.

“Cishe 3ccs [0.10 fl. oz.] izobeka inkomo engu-1,000 pounds phansi, kuyilapho inani elifanayo lingaphumuza ihhashi ngokwanele ukuba lime lapho futhi ligqoke izicathulo,” etshela i-Fox News Digital nge-imeyili.

“Izingxenye ezintathu kweziyishumi ze-cc – inani elincane kakhulu – zizothulisa umuntu ngokugcwele futhi mhlawumbe zibangele ukufa.”

I-TRANQUILIZER YESILWANE ESIXHAYIKWE NESIKHUMBA SE-FENTANYL IBOLA, IJULA ABANTU ‘IBE ‘AMAZOMBI’: ‘ABAFILEYO ABAHAMBAYO’

David I. Deyhimy MD, umuthi wokulutha kanye nodokotela obulala izinzwa ku San Clemente, Californiauma kuqhathaniswa ne-xylazine nomuthi osetshenziselwa izinzwa kubantu okuthiwa i-dexmedetomidine, okuhloswe ngayo ukugcina abantu belele ngesikhathi sokuhlinzwa nezinye izinqubo zezokwelapha.

I-Xylazine ihloselwe ukusetshenziswa odokotela bezilwane njengendlela yokudambisa, ukudambisa izinhlungu kanye/noma isiphumuli semisipha - ngokuvamile ukuthulisa izilwane ngaphambi kokuhlolwa nokuhlinzwa.  Nokho, akuzange kufundwe kubantu, ngakho "akukho umthamo ophephile," kusho omunye umuthi wokulutheka kanye nodokotela obulala izinzwa.

I-Xylazine ihloselwe ukusetshenziswa odokotela bezilwane njengendlela yokudambisa, ukudambisa izinhlungu kanye/noma isiphumuli semisipha – ngokuvamile ukuthulisa izilwane ngaphambi kokuhlolwa nokuhlinzwa. Nokho, ayikahlolisiswa kubantu, ngakho “awukho umthamo ophephile,” kusho omunye umuthi wokulutheka nodokotela obulala izinzwa. (iStock)

“Ngenxa yokuthi akufundwa kubantu, akukho mthamo ophephile owaziwayo,” esho engxoxweni abe nayo neFox News Digital.

I-Narcan ayikwazi ukuguqula ukudlula ngokweqile kwe-xylazine

Nakuba ivame ukuxutshwa nama-opioid, i-xylazine ayiyona i-opioid ngokwayo.

Ngalesi sizathu, Isikhungo Sikazwelonke Sokuxhashazwa Kwezidakamizwa sithi ukweqisa kwezidakamizwa akukwazi ukubhekana ne-naloxone (eyaziwa kakhulu ngamagama omkhiqizo i-Narcan ne-Kloxxado).

Kodwa-ke, lapho i-xylazine ixutshwa ne-fentanyl, i-naloxone ingase ihlehlise i-fentanyl uma inikezwe ngethamo eliphezulu ngokwanele, kusho uDkt. Deyhimy.

Ngenxa yokuthi i-xylazine ayiyona i-opioid, ukweqisa ngokweqile akukwazi ukubhekana ne-naloxone (evame ukwaziwa kakhulu ngamagama ebhrendi i-Narcan ne-Kloxxado).

Ngenxa yokuthi i-xylazine ayiyona i-opioid, ukweqisa ngokweqile akukwazi ukubhekana ne-naloxone (evame ukwaziwa kakhulu ngamagama ebhrendi i-Narcan ne-Kloxxado). (iStock)

“Uma umuntu osebenzisayo engaphenduli futhi enezimpawu zokucindezeleka kokuphefumula noma ukungaphefumuli, i-naloxone kufanele isetshenziswe njalo,” kusho udokotela.

“Awazi ukuthi yini edala ukucindezeleka kokuphefumulakodwa uma i-opioid efana ne-fentanyl ihileleka, i-naloxone izoba usizo futhi ingase isize ukubuyisela ukuphefumula.”

Wanezela, “Umuntu othathe i-xylazine ne-fentanyl angase aqale ukuphefumula futhi ngemva kwe-naloxone – kodwa angase angavuki noma aphendule ngemva kokuphatha.”

“Inani elincane kakhulu lizoqeda ngokuphelele umuntu futhi mhlawumbe libangele ukufa.”

UDkt. Deyhimy waphawula ukuthi i-naloxone ngeke ilimaze abantu abangahlangabezane ne-opioid overdose – kodwa ingasiza labo abanakho, ngisho noma ixutshwe nezinye izidakamizwa ayihlehliswanga yi-naloxone.

I-Xylazine ivame ukuxutshwa nama-opioid

I-Xylazine ivame ukungezwa kwezinye izinto ezingekho emthethweni – ngokuvamile i-fentanyl, kodwa futhi i-heroin, i-cocaine, i-methadone, i-opioid kadokotela nezinye, kusho i-CDC. Lokho kuxutshwa kwenzelwa ukuzuza ukuphakama okude noma ukukhulisa isisindo somuthi ukuze kukhokhiswe inani eliphezulu lawo.

IMITHI YE-OPIOID IBANGELA NGAPHEZU KWEHhafu YOKUFA KWEZINGANE EZINCANE EZINKOSI: UCWANINGO ELISHA

“Uma ixubene nezinye izidakamizwa ezifana ne-fentanyl, i-xylazine yenza imiphumela ethile, njengokudambisa nokucindezeleka kokuphefumula, okwenza inhlanganisela yezidakamizwa ibe yingozi kakhulu kunanoma iyiphi yodwa,” kuxwayisa uDkt. Deyhimy.

"Amaphilisi omgunyathi abukeka afana nalawo okuqala emithi ngokuvamile abangela ukweqisa umthamo nokufa," udokotela utshele iFox News Digital.

“Amaphilisi omgunyathi abukeka afana nawasekuqaleni kwemithi ngokuvamile abangela ukudakwa ngokweqile nokufa,” udokotela etshela iFox News Digital. (iStock)

Udokotela uthe ayikho indlela yokunquma ukuthi i-xylazine ixutshwe nezinye izidakamizwa ngaphandle kokuthi ihlolwe elebhu.

“Njenge-fentanyl nezinye izidakamizwa zokwenziwa, awukwazi ukubikezela ukuthi ikhona futhi ngaliphi inani,” engeza.

Kushibhile futhi kulula ukukuthola

I-Xylazine idayiswa ngokomthetho iwuketshezi kodokotela bezilwane ngokusebenzisa abahlinzeki bemithi.

Kodwa-ke, i-DEA ithi ingabuye ithengwe kalula ku-inthanethi kubahlinzeki bempahla baseShayina iwuketshezi noma impushana ngenani eliphansi elingama-$6 ngekhilogremu.

I-Xylazine ibizwe ngokuthi “isidakamizwa se-zombie” ngenxa yomphumela wayo oseceleni wokubangela ukubola kwenyama.

“Ifomu elimakethwa ngokusemthethweni lodokotela bezilwane liyisixazululo okuhloswe ngaso ukuthi sijovwe, kodwa labo abasebenzisa kabi lesi sidakamizwa bangase bakwazi ukusijova, bawuhlabe, bawugwinye noma bawuhogele,” kusho uDkt Louie.

I-Xylazine inemiphumela eyingozi yokucindezeleka

I-Xylazine iyisimiso sezinzwa esicindezelayo.

Isidakamizwa sisebenza kuma-alpha 2 receptors ebuchosheni ukuze kubangele ukuthuthumela, ukuphumula kwemisipha nokucindezeleka kokuphefumula, kuye ngokuthi umthamo, kusho uDkt Deyhimy.

UKUFA Okuhlobene Ne-FENTANYL AKUNAKAZI EMADOLOBHENI AMAKHULU

“Kungase futhi kubangele umfutho wegazi ophansi, ukwanda noma ukushaya kwenhliziyo kancanekubangele isigqi senhliziyo esingejwayelekile — futhi kungaholela ekuqulekeni nasekufeni,” uxwayise.

Ukwengeza, uDkt. Deyhimy uthe abantu bangahlakulela ukubekezelelana nokuhoxa kanzima ku-xylazine, okungase kubangele ubuhlungu besifuba nokuquleka.

“I-Xylazine ayiphephile ukuthi isetshenziswe kubantu futhi ingase ibe nemiphumela emibi kakhulu nesongela ukuphila ebonakala ifana naleyo. ngokuvamile okuhlotshaniswa nokusetshenziswa kwe-opioidokwenza kube nzima ukuhlukanisa ukweqisa kwe-opioid nokuchayeka kwe-xylazine,” kusho i-FDA ekukhululweni kwabezindaba kuwebhusayithi yayo ngoNovemba 2022.

Kudala ukufa kwabantu ngokweqile

I-National Institute on Drug Abuse ithi ukufa kwe-xylazine ngokweqile kuyanda, okunomthelela omkhulu kakhulu enyakatho-mpumalanga ye-United States.

"I-Xylazine ayiphephile ukusetshenziswa kubantu futhi ingase ibe nemiphumela emibi kakhulu nesongela ukuphila," kusho i-FDA.

“I-Xylazine ayiphephile ukuthi isetshenziswe kubantu futhi ingase ibangele imiphumela emibi kakhulu futhi esongela ukuphila,” kusho i-FDA. (iStock)

E-Pennsylvania, i-xylazine ibandakanyeke ekufeni kwabantu abangaphezu kwengxenye yesine yabo bonke abantu ababulawa ngokweqile ngo-2020, isuka ku-2% kuphela ngo-2015.

E-Maryland, i-19% yokufa ngokweqile kwezidakamizwa ihilela i-xylazine ngo-2021.

Umuthi wawuxhunywe ku-10% wokufa kwe-Connecticut overdose ngo-2020.

Umuthi ungabangela inyama ebolile

I-Xylazine ibizwe ngokuthi “isidakamizwa se-zombie” ngenxa yomphumela wayo oseceleni wokubangela ukubola kwezicubu zomuntu.

“Uma i-xylazine ijovwa, ingabangela amanxeba amabi esikhumbeni, izifo kanye ne-tissue necrosis [death],” UDkt. Deyhimy utshele iFox News Digital.

“Abanye abantu baba namanxeba amabi kangangoba baze badinga ukunqunywa izitho zomzimba.

YIBA KAHLE: I-SPRING-HLANZA IKHABHINETHI YAKHO YEMITHI UKUZE USUSA IMITHI ESEKELWE yisikhathi.

I-FDA ixwayise ngokuthi lezi zilonda zingakhula nakwezinye izindawo zomzimba ngaphandle kwendawo yomjovo.

Konke ukusetshenziswa kwezidakamizwa ezingekho emthethweni manje kuyabulala

Ngokudlanga okwandayo kwezithasiselo eziyingozi njenge-fentanyl ne-xylazine, odokotela baxwayisa ngokuthi noma isiphi isidakamizwa esingekho emthethweni singase sibe yingozi empilweni.

CHOFOZA LAPHA UKUZE Ubhalisele IPHEPHA LETHU LEZEMPILO

“Izidakamizwa zokwenziwa ezinamandla njenge-fentanyl ne-xylazine zonakalisa zonke izidakamizwa ezingekho emthethweni,” kusho uDkt. Deyhimy.

“Amaphilisi omgunyathi abukeka afana nawo imvelaphi yezemithi ngokuvamile kubangela ukweqisa izidakamizwa nokufa.”

I-overdose ye-xylazine iyodwa ayikwazi ukuguqulwa yi-Narcan.

Ubhekisela kulokhu njengobuthi esikhundleni sokusebenzisa izidakamizwa ngokweqile – ngoba izisulu azazi ukuthi zidleni ngempela.

CHOFOZA LAPHA UKUZE UTHOLA UHLELO LOKUSEBENZA IZINDABA ZEZIMpungushe

“Le mishanguzo inamandla kangangoba ukufa kungashona emizuzwini embalwa ngemuva kokuphathwa,” exwayisa.